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e-oligos Oligo Modifications Affinity Ligands Affinity Ligands

Oligonucletides can be labeled with biotin or digoxigenin* or directly labeled with alkaline phosphatase. A variety of linker arms are available as spacers to minimize steric hindrance.

Besides their importance as nucleic acid probes, biotinylated oligonucleotides are also useful for the purification of DNA binding proteins or cognate DNA molecules by specific hybridization based affinity chromatography. The biotinylated oligonucleotide can be bound to a streptavidin matrix and used for either column or spin chromatography.

Modifications for Oligo Synthesis
Product Catalog No. 50 nmol scale (XX=05) 200 nmol scale (XX=02) 1 mmol scale (XX=01) 2 mmol scale (XX=03) 10 mmol scale (XX=10) 15 mmol scale (XX=15)
Biotin 26-6423 $48.00 $48.00 $62.40 $93.60 $499.20
Biotin deoxythymidine dT 26-6424 $325.00 $325.00 $422.50 $633.75 $3,380.00
Biotin multiple additions 26-6421 $324.50 $324.50 $421.85 $632.77 $3,374.80
Biotin NHS 26-6712 $75.00 $250.00 $327.00 $146.25 $780.00
Biotin TEG (15 atom triethylene glycol spacer) 26-6407 $78.00 $78.00 $101.40 $152.10 $811.20
Desthiobiotin NHS 26-6713 $250.00 $250.00 $325.00 $487.50 $2,600.00
Digoxigenin 26-6429 $354.00 $354.00 $460.20 $690.30 $1,884.48
DNP TEG (2, 4-dinitrophenyl) 26-6512 $324.50 $324.50 $421.85 $632.77 $3,374.80
NTA (Nitrilotriacetate) Oligo Conjugate 26-6444 $350.00 $350.00 $625.00 $937.00 $4,400.00
pseudoUridine ribo (psi rU) 27-6531 $350.00 $350.00 $455.00 $682.50 $3,640.00
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