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Oligo Modifications List | Oligo Modifications Reference Category
Modification : Cholesterol TEG
Reference Catalog Number 26-6602
Category Conjugation Chemistry & End Modifiers
Modification Code CholTEG
5 Prime Y
3 Prime Y
Internal Y
Molecular Weight (mw) 755.97
Technical Info (pdf) PS26-6602.pdf
Catalog NoScalePrice
26-6602-0550 nmol$175.00
26-6602-02200 nmol$175.00
26-6602-011 umol$210.00
26-6602-032 umol$265.00
26-6602-1010 umol$987.00
26-6602-1515 umol$126.00

Discounts are available for Cholesterol TEG!
Modification* Discount Price Structure
1 site/order List price
2 sites/order 10% discount
3 sites/order 20% discount
4 sites/order 30% discount
5-9 sites/order 50% discount
10+ sites/order 60% discount
*Exceptions apply

Potential therapeutic oligonucleotides must permeate the cell membrane for optimal activity. The addition of lipophilic groups to an oligonucleotide would be expected to enhance activity. The use of cholesteryl oligos and the consequent improvement in activity has been described. We have designed our Cholesteryl Phosphoramidite with our branched triethyleneglycol (TEG) spacer for maximum solubility in acetonitrile as well as for applications requiring multiple labels.
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