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Oligo Modifications List | Oligo Modifications Reference Category
Modification : Amino C6 U
Reference Catalog Number 27-6422
Category Minor Bases
Modification Code Amino C6 U
5 Prime Y
3 Prime Y
Internal Y
Molecular Weight (mw) 474.4
Extinction Coeficient (ec) 8.4
Technical Info (pdf) PS26-6438-02.pdf
Catalog NoScalePrice
27-6422-0550 nmol$220.50
27-6422-02200 nmol$220.50
27-6422-011 umol$256.65
27-6422-032 umol$319.97
27-6422-1010 umol$2,293.20
27-6422-1515 umol$2,866.50

Discounts are available for Amino C6 U !
Modification* Discount Price Structure
1 site/order List price
2 sites/order 10% discount
3 sites/order 20% discount
4 sites/order 30% discount
5-9 sites/order 50% discount
10+ sites/order 60% discount
*Exceptions apply

Related Modifications
Amino dA C6
Amino C6
Amino Serinol
Amino C7
Amino dT C6
Amino dG C6
Amino C3
Amino dC C6
Amino C12

Amino C6-U can be used to internally incorporate an active primary amino group into either an RNA oligonucleotide or a chimeric oligo. The presence of the primary amino group allows the user to label the oligo with a variety of different ligands for affinity, reporter or protein moieties (as NHS esters or isothiocyanates), depending on the application. Examples include biotin, digoxigenin, and fluorescent dyes or quenchers, magnetic beads and enzymes (for example, alkaline phosphatase).


The primary amine labelled oligos can also be conjugated to carboxyl functional groups usually for solid supports applications using EDC mediated reaction as shown in the figure below.


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