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Oligo Modifications List | Oligo Modifications Reference Category
Modification : ddG-5'
Reference Catalog Number 26-6338
Category End Blockers
Modification Code ddG-5'
5 Prime Y
3 Prime N
Internal N
Molecular Weight (mw) 313.2
Extinction Coeficient (ec) 11.5
Technical Info (pdf) PS26-6338.pdf
Catalog NoScalePrice
26-6338-0550 nmol$275.00
26-6338-02200 nmol$275.00
26-6338-011 umol$412.00
26-6338-032 umol$742.00
26-6338-1010 umol$3,296.00
26-6338-1515 umol$4,120.00

Discounts are available for ddG-5'!
Modification* Discount Price Structure
1 site/order List price
2 sites/order 10% discount
3 sites/order 20% discount
4 sites/order 30% discount
5-9 sites/order 50% discount
10+ sites/order 60% discount
*Exceptions apply

Related Modifications
ddA-5'
ddG-5'
ddT-5'
ddC-3'
ddC-5'

Dideoxyguanosine (ddG) is a dideoxyribonucleoside that can only be used to block the 5' end. Use ddC-3' or Spacer C3 to block the 3' end from polymerase extension. ddG is a synthetic analog of deoxyguanosine, in ddG, both the 2’- and 3’-positions of the ribose have a hydrogen (-H) group substituted for the –OH group, whereas in dG, only the 2’-position is so substituted. ddG is added to the 5’-end of an oligo via 5’-to-5’ synthesis, using a 2’,3’-ddG, 5’-phosphoramidite. Purification must be by PAGE purification, since such an oligo will not have a trityl group (necessary for RPC purification).

ddC-3' should be used as a 3’-end blocking moiety (see ddC technical sheet).

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