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Oligo Modifications List | Oligo Modifications Reference Category
Modification : ddA-5'
Reference Catalog Number 26-6331
Category End Blockers
Modification Code ddA-5'
5 Prime Y
3 Prime N
Internal N
Molecular Weight (mw) 297.21
Extinction Coeficient (ec) 15.4
Technical Info (pdf) PS26-6331.pdf
Catalog NoScalePrice
26-6331-0550 nmol$195.00
26-6331-02200 nmol$195.00
26-6331-011 umol$292.00
26-6331-032 umol$438.00
26-6331-1010 umol$2,336.00
26-6331-1515 umol$2,920.00

Discounts are available for ddA-5'!
Modification* Discount Price Structure
1 site/order List price
2 sites/order 10% discount
3 sites/order 20% discount
4 sites/order 30% discount
5-9 sites/order 50% discount
10+ sites/order 60% discount
*Exceptions apply

Related Modifications
ddG-5'
ddT-5'
ddC-3'
ddC-5'

Dideoxyadenosine (ddA) is a dideoxyribonucleoside that can only be used to block the 5' end. Use ddC-3' or Spacer C3 to block the 3' end from polymerase extension. ddA is a synthetic analog of deoxyadenosine, in ddA, both the 2’- and 3’-positions of the ribose have a hydrogen (-H) group substituted for the –OH group, whereas in dA, only the 2’-position is so substituted. ddA is added to the 5’-end of an oligo via 5’-to-5’ synthesis, using a 2’,3’-ddA, 5’-phosphoramidite. Purification must be by PAGE purification, since such an oligo will not have a trityl group (necessary for RPC purification).

ddC-3' should be used as a 3’-end blocking moiety (see ddC technical sheet).

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