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Oligo Modifications List | Oligo Modifications Reference Category
Modification : N-POM Caged-dT
Reference Catalog Number 26-6563
Category Structural Studies
Modification Code N-POM-Cg-dT
5 Prime Y
3 Prime Y
Internal Y
Molecular Weight (mw) 527.38
Extinction Coeficient (ec) 8.4
Technical Info (pdf) PS26-6563.pdf
Catalog NoScalePrice
26-6563-0550 nmol$355.00
26-6563-02200 nmol$355.00
26-6563-011 umol$461.50
26-6563-032 umol$692.25
26-6563-1010 umol$3,692.00
26-6563-1515 umol$4,615.00

Discounts are available for N-POM Caged-dT!
Modification* Discount Price Structure
1 site/order List price
2 sites/order 10% discount
3 sites/order 20% discount
4 sites/order 30% discount
5-9 sites/order 50% discount
10+ sites/order 60% discount
*Exceptions apply

Photo Activation Modification

N-POM Caged-dT can be used in the synthesis of caged oligonucleotides whose function is restored after uncaging by UV light at a wavelength that causes no DNA damage. The NPOM-Caged-dT, where the nucleobase is caged with the photolabile group, 6-nitropiperonyloxymethyl (NPOM), which can be removed using UV light at 365nm. Oligonucleotides containing NPOM-Caged-dT every five or six bases do not hybridize to their complementary strand. Photo-uncaging of the caged oligonucleotide is then easily carried out with UV light at 365 nm for seconds to minutes to restore the activity of the oligonucleotide.

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