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Oligo Modifications List | Oligo Modifications Reference Category
Modification : Acrydite 5'
Reference Catalog Number 26-6999
Category Others
Modification Code 5Acryd
5 Prime Y
3 Prime N
Internal N
Molecular Weight (mw) 247.2
Technical Info (pdf) PS26-6999.PDF
Catalog NoScalePrice
26-6999-0550 nmol$143.00
26-6999-02200 nmol$143.00
26-6999-011 umol$150.00
26-6999-032 umol$225.00
26-6999-1010 umol$600.00
26-6999-1515 umol$900.00

Discounts are available for Acrydite 5'!
Modification* Discount Price Structure
1 site/order List price
2 sites/order 10% discount
3 sites/order 20% discount
4 sites/order 30% discount
5-9 sites/order 50% discount
10+ sites/order 60% discount
*Exceptions apply

Acrydite is a modification that allows the synthesis of oligonucleotides with a methacryl group at the 5' end. Acryl oligonucleotides have been tested, but the acryl group is not stable to storage. Acrydite modified oligonucleotides can react with nucleophiles such as thiols (Michael addition chemistry), this forms the basis of the ez-rays chemistry which was used for microarrays. More importantly, Acrydite modified oligonucleotides can be incorporated, stoichiometrically, into hydrogels such as polyacrylamide, using standard free radical polymerization chemistry, where the double bond in the Acrydite group reacts with other activated double bond containing compounds such as acrylamide.
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