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Oligo Modifications List | Oligo Modifications Reference Category
Modification : rN RNA Bases
Reference Catalog Number 27-6400N
Category RNA Oligo Synthesis
Modification Code rN
5 Prime Y
3 Prime Y
Internal Y
Molecular Weight (mw) 330
Technical Info (pdf) PS27-6400N.pdf
Catalog NoScalePrice
27-6400N-0550 nmol$6.25
27-6400N-02200 nmol$8.25
27-6400N-011 umol$14.40
27-6400N-032 umol$28.00
27-6400N-1010 umol$118.00
27-6400N-1515 umol$192.00
Related Modifications
3'-O methyl bases
rN RNA Bases
2'-F Bases
2'-MOE- Bases
2'-O methyl bases

RNA contains a ribose sugar instead of a deoxyribose and a Uracil bases instead of Thymine in DNA. The presence of the –OH group at the 2’-position of the ribose results in RNA being less stable to DNA (which lacks –OH groups at this position), because this 2’-hydroxyl group can chemically attack the adjacent phosphodiester bond in the sugar-phosphate backbone of RNA, leading to cleavage of the backbone structure. rA forms a Watson-Crick base pair with rU (ribouridine/uridine) in RNA duplexes, and dT (deoxythymidine) in RNA-DNA duplexes.


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