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Oligo Modifications List | Oligo Modifications Reference Category
Modification : rC RNA Base
Reference Catalog Number 27-6400C
Category RNA Oligo Synthesis
Modification Code rC
5 Prime Y
3 Prime Y
Internal Y
Molecular Weight (mw) 305.18
Extinction Coeficient (ec) 7.4
Technical Info (pdf) PS27-6400-.pdf
Catalog NoScalePrice
27-6400C-5050 nmol$6.25
27-6400C-02200 nmol$8.25
27-6400C-011 umol$14.40
27-6400C-032 umol$28.00
27-6400C-1010 umol$118.00
27-6400C-1515 umol$192.00

Ribocytosine, or cytosine (rC) is a pyrimidine ribonucleoside, and is one of the four standard nucleosides that compose an RNA molecule. The presence of the –OH group at the 2’-position of the ribose results in RNA being less stable to DNA (which lacks –OH groups at this position), because this 2’-hydroxyl group can chemically attack the adjacent phosphodiester bond in the sugar-phosphate backbone of RNA, leading to cleavage of the backbone structure. rC forms a Watson-Crick base pair with rG (riboguanosine/guanosine) in RNA duplexes, or dG (deoxyriboguanosine) in RNA-DNA duplexes.


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