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Oligo Modifications List | Oligo Modifications Reference Category
Modification : rU RNA Base
Reference Catalog Number 27-6400U
Category RNA Oligo Synthesis
Modification Code rU
5 Prime Y
3 Prime Y
Internal Y
Molecular Weight (mw) 306.17
Extinction Coeficient (ec) 9.9
Technical Info (pdf) PS27-6400-.pdf
Catalog NoScalePrice
27-6400U-0550 nmol$6.25
27-6400U-02200 nmol$8.25
27-6400U-011 umol$14.40
27-6400U-032 umol$28.00
27-6400U-1010 umol$118.00
27-6400U-1515 umol$192.00

Ribouridine, or uridine (rU) is a purine ribonucleoside, and is one of the four standard ribonucleosides that compose an RNA molecule. The presence of the –OH group at the 2’-position of the ribose results in RNA being less stable to DNA (which lacks –OH groups at this position), because this 2’-hydroxyl group can chemically attack the adjacent phosphodiester bond in the sugar-phosphate backbone of RNA, leading to cleavage of the backbone structure. rU forms a Watson-Crick base pair with rA (riboadensoine/adenosine) in RNA duplexes, and dA (deoxyadenosine) in RNA-DNA duplexes.

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